Hasn't every woman ever wondered whether it's best to ditch all the men and just marry your best friend? Paula and Emily are doing just that. Single hotel owner Paula Atkinson and her impulsive friend Emily van Garden have known each other since high school and have always been able to rely on each other. In a love crisis, Emily therefore moves into the "Seaside Hotel" and supports Paula. When Emily catches her fiancé Frank with someone else a few days before the wedding and Paula realizes after an upsetting visit to the doctor that no one will be there for her nine-year-old daughter Lucy in an emergency, the two spontaneously order the posse in a two-girlfriends-against-the-rest-of-the-world moment.

Grace Ravenglass is the owner of Luckenham House, an estate in the picturesque Hudson Valley near the metropolis of New York. Grace is just about to break up her marriage and has to come to terms with her husband Edward moving out to be with his younger lover when she meets Ellie Summers. The young artist earns her living with commissioned drawings of private houses. She also offers her services to Grace. As different as the women seem, they like each other straight away. Grace understands how Ellie feels, having been left pregnant by her boyfriend, and offers her a place to stay at Luckenham.

Harriet Devonshire left school because of her unwed pregnancy and still lives with her dad Ronald. Only when he arranges for her teenage son Matthew to be enrolled in the same boarding school without consulting her, she leaves, only to find he obtains custody and she stands no chance of contesting it without a steady job. New York star photographer Leo Purbright takes her on as factotum, perhaps a shot at a real career, but his jealous assistant adds to the practical problems to square work with Matthew's present needs, miserable as bully Tommy's picked target.

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Lifelong best friends Alexa and Katie are eagerly anticipating the start of their freshman year of high school. The pals confront a crisis that leaves them feeling like outsiders at a time when what seems to matter most is fitting in.

Two mismatched women are on the run from gangsters and must help one another to survive.

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